The mechanism of action of iNPWT*1-9 ：
Handling
● Hygienic wound closure—bacteria proof wound dressing for sealing the wound so no external bacteria can enter the wound and the patient’s own wound bacteria are not spread. This is particularly important in the event of contamination with problematic bacteria, as in patients with meticillin-resistant Staphylococcus aureus (MRSA)-infected wounds. Thus, italso reduces the risk of cross-infections and development of resistance within the hospital
● Transparent dressing permits continuous clinical monitoring of the surrounding skin through the film with which the wound has been sealed
● Odourless and hygienic dressing technique; constant seeping through the dressing onto the patient’s clothing and bedding can be avoided, reducing demands on the nursing staff
● Reduction in the number of required dressing changes (only necessary every two to three days), which reduces nursing time requirements, particularly in patients with exudating wounds.
● Reduction of interstitial
oedema
● Consecutive improvement of
microcirculation, stimulation of
blood flow and oxygenation.
● Wound retraction,
Stimulation of granulation
tissue formation
● Removal of small tissue
debris by suction,reduce wound
infection.
● Continuous removal of wound exudate,
Creating a moist wound environment
● Sealing the wound, Isolating the wound from
infection of externalorigin
1. Fleischmann, W., Becker, U., Bischoff, M., Hoekstra, H. Vacuum sealing: indications, technique and results. Eur J Orthop Surg Traumatol 1995; 5: 37–40. Medline doi:10.1007/BF02716212
2. Argenta, L.C., Morykwas, M.J. Vacuum-assisted closure: a new method for wound control and treatment: clinical experience. Ann Plast Surg 1997; 38: 6, 563–577.
3. Banwell, P.E., Teot, L. Topical negative pressure (TNP): the evolution of a novel wound therapy. J Wound Care 2003; 12: 1, 22–28.
4. Armstrong, D.G., Lavery, L.A., Abu-Rumman, P. et al. Outcomes of subatmospheric pressure dressing therapy on wounds of the diabetic foot. Ostomy Wound Manage 2002; 48: 4, 64–68.
5. Deva, A.K., Buckland, G.H., Fisher, E. et al. Topical negative pressure in
wound management. Med J Aust 2000; 173: 3, 128–131.
6. Avery, C., Pereira, J., Moody, A., Whitworth, I. Clinical experience with the negative pressure wound dressing. Br J Oral Maxillofac Surg 2000; 38: 4, 343–345. Medline doi:10.1054/bjom.1999.0453
7. Banwell, P.E. Topical negative pressure therapy in wound care. J Wound Care 1999; 8: 2, 79–84.
8. Banwell, P., Holten, I., Martin, D.L. Negative pressure therapy: clinical applications and experience with 200 cases. Wound Repair Regen 1998; 6: 460.
9. Fleischmann, W., Lang, E., Russ, M. [Treatment of infection by vacuum sealing]. [Article in German] Unfallchirurg 1997; 100: 4, 301–304.
Patient comfort
● Easy and early patient mobilisation
● Visually appealing dressing method due to clean, exudate-free dressing conditions even during mobilisation.
● (Chronic disease management) Appropriate exercise is beneficial for blood sugar and blood pressure control
● (Nutrition improvement) In-hospital activities or Wound homeCare improves the quality of life of patients and improves nutrient intake and absorption
● (Relieving anxiety, depression) Enhances the confidence of patients to heal and shape a positive therapeutic attitude
● (Reduced medication and complications) In-hospital activities or Wound homeCare , reducing medication and allergic reactions, avoiding complications caused by prolonged bed rest
Effect on the wound
● Reduction of the wound area due to negative pressure acting on the foam, pulls together the edges of the wound (wound retraction)
● Stimulation of granulation tissue formation in an optimally moist wound environment; in several situations even over bradytrophic tissue such as tendons and bone NPWT was able to stimulate granulation tissue formation
● Continuation of effective mechanical wound cleansing (removal of small tissue debris by suction)
● Effective biochemical reduction of the fluid concentration of wound healing-impairing proteases (such as elastase)—in the first days
● Reliable, continuous removal of wound exudate (and, consequently, fewer dressing changes) within a closed system
● Pressure-related reduction of interstitial oedema with consecutive improvement of microcirculation, stimulation of blood flow and oxygenation.
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